Karyopharm Therapeutics Stock Analysis

KPTI Stock  USD 4.76  0.74  18.41%   
Karyopharm Therapeutics is undervalued with Real Value of 10.78 and Target Price of 29.25. The main objective of Karyopharm Therapeutics stock analysis is to determine its intrinsic value, which is an estimate of what Karyopharm Therapeutics is worth, separate from its market price. There are two main types of Karyopharm Therapeutics' stock analysis: fundamental analysis and technical analysis.
The Karyopharm Therapeutics stock is traded in the USA on NASDAQ Exchange, with the market opening at 09:30:00 and closing at 16:00:00 every Mon,Tue,Wed,Thu,Fri except for officially observed holidays in the USA. Here, you can get updates on important government artifacts, including earning estimates, SEC corporate filings, announcements, and Karyopharm Therapeutics' ongoing operational relationships across important fundamental and technical indicators.
Check out Correlation Analysis to better understand how to build diversified portfolios, which includes a position in Karyopharm Therapeutics. Also, note that the market value of any company could be closely tied with the direction of predictive economic indicators such as signals in estimate.
For more detail on how to invest in Karyopharm Stock please use our How to Invest in Karyopharm Therapeutics guide.

Karyopharm Stock Analysis Notes

About 43.0% of the company shares are owned by institutional investors. The company recorded a loss per share of 11.49. Karyopharm Therapeutics had not issued any dividends in recent years. The entity had 1:15 split on the 26th of February 2025. Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. The company was incorporated in 2008 and is headquartered in Newton, Massachusetts. Karyopharm Therapeut operates under Biotechnology classification in the United States and is traded on NASDAQ Exchange. It employs 442 people. To find out more about Karyopharm Therapeutics contact Richard MBA at 617 658 0600 or learn more at https://www.karyopharm.com.

Karyopharm Therapeutics Quarterly Total Revenue

30.02 Million

Karyopharm Therapeutics Investment Alerts

Karyopharm Therapeutics generated a negative expected return over the last 90 days
Karyopharm Therapeutics has high historical volatility and very poor performance
Karyopharm Therapeutics has a very high chance of going through financial distress in the upcoming years
The company reported the previous year's revenue of 145.24 M. Net Loss for the year was (76.42 M) with profit before overhead, payroll, taxes, and interest of 137.54 M.
Karyopharm Therapeutics currently holds about 170.85 M in cash with (127.49 M) of positive cash flow from operations. This results in cash-per-share (CPS) ratio of 2.14.
Karyopharm Therapeutics has a poor financial position based on the latest SEC disclosures
Latest headline from thelincolnianonline.com: Karyopharm Therapeutics Downgraded to Neutral Rating by HC Wainwright

Karyopharm Therapeutics Upcoming and Recent Events

Every quarterly earnings report provides investors with three things: an overview of sales, expenses, and net income for the most recent period. It also may provide a comparison to Karyopharm Therapeutics previous reporting period. The quarterly earnings reports are usually disseminated to the public via Form 10-Q, which is a legal document filed with the Securities and Exchange Commission every quarter.
21st of February 2024
Upcoming Quarterly Report
View
2nd of May 2024
Next Financial Report
View
31st of December 2023
Next Fiscal Quarter End
View
21st of February 2024
Next Fiscal Year End
View
30th of September 2023
Last Quarter Report
View
31st of December 2022
Last Financial Announcement
View

Karyopharm Largest EPS Surprises

Earnings surprises can significantly impact Karyopharm Therapeutics' stock price both in the short term and over time. Negative earnings surprises usually result in a price decline. However, it has been seen that positive earnings surprises lead to an immediate rise in a stock's price and a gradual increase over time. This is why we often hear news about some companies beating earning projections. Financial analysts spend a large amount of time predicting earnings per share (EPS) along with other important future indicators. Many analysts use forecasting models, management guidance, and additional fundamental information to derive an EPS estimate.
Reported
Fiscal Date
Estimated EPS
Reported EPS
Surprise
2025-02-26
2024-12-31-0.2688-0.240.028810 
2024-02-29
2023-12-31-0.31-0.36-0.0516 
2023-08-02
2023-06-30-0.34-0.290.0514 
View All Earnings Estimates

Karyopharm Therapeutics Environmental, Social, and Governance (ESG) Scores

Karyopharm Therapeutics' ESG score is a quantitative measure that evaluates Karyopharm Therapeutics' performance and commitment regarding environmental, social, and governance (ESG) factors. These scores are becoming increasingly crucial in investment decision-making processes, providing insights into non-financial aspects of Karyopharm Therapeutics' operations that may have significant financial implications and affect Karyopharm Therapeutics' stock price as well as guide investors towards more socially responsible investments.

Karyopharm Therapeutics Thematic Classifications

In addition to having Karyopharm Therapeutics stock in your portfolios, you can add positions using our predefined set of ideas and optimize them against your very unique investing style. A single investing idea is a collection of funds, stocks, ETFs, or cryptocurrencies that are programmatically selected from a pull of investment themes. After you determine your favorite investment opportunity, you can then obtain an optimal portfolio that will maximize potential returns on the chosen idea or minimize its exposure to market volatility. If you are a result-oriented investor, you can benefit from optimizing one of our existing themes to build an efficient portfolio against your specific investing outlook.
Cancer Fighters Idea
Cancer Fighters
Public companies from health care and pharmaceutical sectors that are focused on fighting cancer

Karyopharm Stock Institutional Investors

Shares
Bank Of America Corp2025-03-31
132.9 K
Marshall Wace Asset Management Ltd2025-03-31
128.5 K
Cam Group Holding A/s2025-03-31
100 K
Geode Capital Management, Llc2025-03-31
99.6 K
Ubs Group Ag2025-03-31
93.6 K
Goldman Sachs Group Inc2025-03-31
85.4 K
Renaissance Technologies Corp2025-03-31
61.2 K
Millennium Management Llc2025-03-31
55.4 K
Silverback Aset Management Llc2025-03-31
50 K
Palo Alto Investors, Llc2024-12-31
4.9 M
Vanguard Group Inc2025-03-31
510.3 K
Note, although Karyopharm Therapeutics' institutional investors appear to be way more sophisticated than retail investors, it remains unclear if professional active investment managers can reliably enhance risk-adjusted returns by an amount that exceeds fees and expenses.

Karyopharm Market Capitalization

The company currently falls under 'Micro-Cap' category with a current market capitalization of 34.73 M.

Karyopharm Profitablity

The company has Profit Margin (PM) of (0.44) %, which may suggest that it does not properly executes on its current pricing strategies or is unable to control all of the operational costs. This is way below average. Similarly, it shows Operating Margin (OM) of (1.11) %, which suggests for every $100 dollars of sales, it generated a net operating loss of $1.11.
Last ReportedProjected for Next Year
Return On Tangible Assets(0.46)(0.49)
Return On Capital Employed(1.66)(1.57)
Return On Assets(0.46)(0.49)
Return On Equity 0.41  0.43 

Management Efficiency

Karyopharm Therapeutics has return on total asset (ROA) of (0.4476) % which means that it has lost $0.4476 on every $100 spent on assets. This is way below average. Similarly, it shows a return on stockholder's equity (ROE) of (8.9105) %, meaning that it created substantial loss on money invested by shareholders. Karyopharm Therapeutics' management efficiency ratios could be used to measure how well Karyopharm Therapeutics manages its routine affairs as well as how well it operates its assets and liabilities. The Karyopharm Therapeutics' current Return On Equity is estimated to increase to 0.43, while Return On Tangible Assets are projected to decrease to (0.49). As of now, Karyopharm Therapeutics' Asset Turnover is increasing as compared to previous years.
Last ReportedProjected for Next Year
Book Value Per Share(22.90)(21.75)
Tangible Book Value Per Share(22.90)(21.75)
Enterprise Value Over EBITDA(5.55)(5.83)
Price Book Value Ratio(0.44)(0.42)
Enterprise Value Multiple(5.55)(5.83)
Price Fair Value(0.44)(0.42)
Enterprise Value201.3 M191.2 M
Understanding the operational decisions made by Karyopharm Therapeutics management offers insights into its financial robustness. This evaluation is crucial for assessing the stock's investment potential.
Operating Margin
(1.11)
Profit Margin
(0.44)
Beta
0.246
Return On Assets
(0.45)
Return On Equity
(8.91)

Technical Drivers

As of the 23rd of July, Karyopharm Therapeutics secures the Mean Deviation of 4.4, downside deviation of 5.87, and Risk Adjusted Performance of 0.0215. Karyopharm Therapeutics technical analysis lets you operate historical price patterns with an objective to determine a pattern that forecasts the direction of the firm's future prices.

Karyopharm Therapeutics Price Movement Analysis

The output start index for this execution was thirty-two with a total number of output elements of twenty-nine. The MESA Adaptive Moving Average indicator adapts to Karyopharm Therapeutics price movement based on the rate change of phase as measured by the Hilbert Transform Discriminator.

Karyopharm Therapeutics Insider Trading Activities

Some recent studies suggest that insider trading raises the cost of capital for securities issuers and decreases overall economic growth. Trading by specific Karyopharm Therapeutics insiders, such as employees or executives, is commonly permitted as long as it does not rely on Karyopharm Therapeutics' material information that is not in the public domain. Local jurisdictions usually require such trading to be reported in order to monitor insider transactions. In many U.S. states, trading conducted by corporate officers, key employees, directors, or significant shareholders must be reported to the regulator or publicly disclosed, usually within a few business days of the trade. In these cases Karyopharm Therapeutics insiders are required to file a Form 4 with the U.S. Securities and Exchange Commission (SEC) when buying or selling shares of their own companies.
 
Bohlin Garen G over three weeks ago
Acquisition by Bohlin Garen G of 4600 shares of Karyopharm Therapeutics at 4.48 subject to Rule 16b-3
 
Bohlin Garen G over a month ago
Acquisition by Bohlin Garen G of 4600 shares of Karyopharm Therapeutics at 4.48 subject to Rule 16b-3
 
Paulson Richard A. over two months ago
Disposition of 236 shares by Paulson Richard A. of Karyopharm Therapeutics at 7.12 subject to Rule 16b-3
 
Rangwala Reshma over three months ago
Disposition of 419 shares by Rangwala Reshma of Karyopharm Therapeutics at 6.17 subject to Rule 16b-3
 
Paulson Richard A. over three months ago
Disposition of 245 shares by Paulson Richard A. of Karyopharm Therapeutics at 3.74 subject to Rule 16b-3
 
Mano Michael over three months ago
Acquisition by Mano Michael of 9167 shares of Karyopharm Therapeutics subject to Rule 16b-3
 
Mirza Mansoor Raza over three months ago
Acquisition by Mirza Mansoor Raza of 69000 shares of Karyopharm Therapeutics at 0.96 subject to Rule 16b-3
 
Mano Michael over three months ago
Disposition of 2793 shares by Mano Michael of Karyopharm Therapeutics at 6.29 subject to Rule 16b-3
 
Mano Michael over three months ago
Acquisition by Mano Michael of 4500 shares of Karyopharm Therapeutics at 7.95 subject to Rule 16b-3
 
Paulson Richard A. over three months ago
Disposition of 4099 shares by Paulson Richard A. of Karyopharm Therapeutics at 0.65 subject to Rule 16b-3
 
Macomber Lori over three months ago
Acquisition by Macomber Lori of 160000 shares of Karyopharm Therapeutics subject to Rule 16b-3
 
Paulson Richard A. over six months ago
Disposition of 4055 shares by Paulson Richard A. of Karyopharm Therapeutics at 0.783 subject to Rule 16b-3

Karyopharm Therapeutics Outstanding Bonds

Karyopharm Therapeutics issues bonds to finance its operations. Corporate bonds make up one of the largest components of the U.S. bond market, which is considered the world's largest securities market. Karyopharm Therapeutics uses the proceeds from bond sales for a wide variety of purposes, including financing ongoing mergers and acquisitions, buying new equipment, investing in research and development, buying back their own stock, paying dividends to shareholders, and even refinancing existing debt. Most Karyopharm bonds can be classified according to their maturity, which is the date when Karyopharm Therapeutics has to pay back the principal to investors. Maturities can be short-term, medium-term, or long-term (more than ten years). Longer-term bonds usually offer higher interest rates but may entail additional risks.

Karyopharm Therapeutics Predictive Daily Indicators

Karyopharm Therapeutics intraday indicators are useful technical analysis tools used by many experienced traders. Just like the conventional technical analysis, daily indicators help intraday investors to analyze the price movement with the timing of Karyopharm Therapeutics stock daily movement. By combining multiple daily indicators into a single trading strategy, you can limit your risk while still earning strong returns on your managed positions.

Karyopharm Therapeutics Forecast Models

Karyopharm Therapeutics' time-series forecasting models are one of many Karyopharm Therapeutics' stock analysis techniques aimed at predicting future share value based on previously observed values. Time-series forecasting models ae widely used for non-stationary data. Non-stationary data are called the data whose statistical properties e.g. the mean and standard deviation are not constant over time but instead, these metrics vary over time. These non-stationary Karyopharm Therapeutics' historical data is usually called time-series. Some empirical experimentation suggests that the statistical forecasting models outperform the models based exclusively on fundamental analysis to predict the direction of the market movement and maximize returns from investment trading.

About Karyopharm Stock Analysis

Stock analysis is the technique used by a trader or investor to examine and evaluate how Karyopharm Therapeutics prices is reacting to, or reflecting on a current market direction and economic conditions. It can be used to make informed decisions about market timing, and when buying or selling Karyopharm shares will generate the highest return on investment. We also built our stock analysis module to help investors to gain an insight into the world economy as a whole, the stock market, thematic ideas. a specific sector, or an individual Stock such as Karyopharm Therapeutics. By using and applying Karyopharm Stock analysis, traders can create a robust methodology for identifying Karyopharm entry and exit points for their positions.
Last ReportedProjected for Next Year
Pretax Profit Margin(0.53)(0.55)
Operating Profit Margin(0.82)(0.86)
Net Loss(0.53)(0.55)
Gross Profit Margin 0.96  1.01 

Current Karyopharm Analysis - Recommendations

We track the performance of the top 100 financial experts across various large and mid-size financial boutiques. Karyopharm analyst recommendations are determined by taking all analyst recommendations and averaging them as Strong Buy, Buy, Hold, Strong Sell or Sell. There is no one specific way to measure analysis performance other than comparing it to the past results via a very sophisticated attribution analysis. Karyopharm analyst consensus and target price projections should be used in combination with other traditional techniques such as stock price forecasting, technical analysis, earnings estimate, and various momentum models.
Target PriceAdvice# of Analysts
29.25Strong Buy6Odds
Karyopharm Therapeutics current and past analyst recommendations published by a number of research institutions as well as average analyst consensus.
Most Karyopharm analysts issue ratings four times a year, at intervals of three months. Ratings are usually accompanied by a target price to helps potential investors understand Karyopharm stock's fair price compared to its market value. Analysts arrive at stock ratings after researching public financial statements of Karyopharm Therapeutics, talking to its executives and customers, or listening to Karyopharm conference calls.
Karyopharm Analyst Advice Details

Karyopharm Stock Analysis Indicators

Karyopharm Therapeutics stock analysis indicators help investors evaluate how Karyopharm Therapeutics stock reacts to ongoing and evolving market conditions. The investors can use it to make informed decisions about market timing and determine when trading Karyopharm Therapeutics shares will generate the highest return on investment. By understating and applying Karyopharm Therapeutics stock analysis, traders can identify Karyopharm Therapeutics position entry and exit signals to maximize returns.
Begin Period Cash Flow53.2 M
Long Term Debt162.9 M
Common Stock Shares Outstanding4.1 M
Total Stockholder Equity-186 M
Total Cashflows From Investing Activities95.5 M
Tax Provision57 K
Property Plant And Equipment Net6.3 M
Cash And Short Term Investments108.7 M
Cash62.5 M
Accounts Payable5.1 M
Net Debt132 M
50 Day M A4.6033
Total Current Liabilities92.3 M
Other Operating Expenses264.7 M
Non Current Assets Total7.9 M
Non Currrent Assets Other1.6 M
Stock Based Compensation18.4 M

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